Recombinant Human Sirtuin 5 Protein (SIRT5), Biotinylated

SIRT5 (Sirtuin 5) is a key member of the SIR2 / Sirtuin family of nicotinamide adenine dinucleotide (NAD-dependent) deacetylase enzymes. Found across the cytoplasm, mitochondria, and nucleus, SIRT5 exhibits critical enzymatic activities, including NAD-dependent lysine demalonylase, desuccinylase, and deglutarylase functions that remove malonyl, succinyl, and glutaryl modifications on target proteins.

This active recombinant human SIRT5 protein features an N-terminal AviTag™ peptide and His-tag. It is expressed in E. coli cells and site-specifically biotinylated using the BirA enzyme, making it ideal for robust, high-throughput NAD-dependent demalonylase and desuccinylase screening assays, binding studies, and Western blot controls.

• Catalog #: SIRT5-B-301
• Application: For laboratory research use only.