Silica Coated Magnetic Nanoparticles | RNA Extraction

Description:

 Amid Biosciences’ SilaMag Nanoparticles are produced by employing a modified Stoeber process by hydrolysis of orthosilicates on magnetite surface. Silica coating improves stability and shelf life of the magnetic NanoBeads.

The surface of SilaMag Nanoparticles contains terminal Si-OH bonds facilitating hydrophilic properties. Additionally, Si-OH bonds enable the surface functionalization by offering diverse active groups including NH2, COOH, SH, N-hydroxysuccinimide (NHS) and epoxy for the covalent binding of proteins, antibodies, DNAs, RNAs and other molecules.    

 Properties:

SilaMag Nanoparticles are stable in water and common buffers.

Specification:

• Size: ~ 400 nm
• Concentration: 10 mg/ml
• pH: 7.0
• Density: 1.3 g/ml

 Applications:

SilaMag NanoBeads allow quick separation from solution.

• clean-up and size exclusion procedures,
• plasmid DNA extractions,
• isolation of total nucleic acids from mammalian cells,
• gDNA extraction,
• RNA from mammalian cells,
• methylated DNA extraction.

Storage/Stability

Suspension in water. The suspension should be stable approximately one year stored at 2-8 °C.

Precautions and Disclaimer

SilaMag Nanoparticles for laboratory use only; not for diagnostic, drug, household or other uses. Please refer to the Material Safety Data Sheet (MSDS).

Catalog # SN-101-1 and SN-101-5