GlycFree (λDE3) Competent Cells for Expression of non-glycosylated recombinant proteins | Chemically competent
High-efficiency Chemically competent E. coli cells optimized for Non-glycosylated recombinant protein expression, Sugar-free protein expression, T7 promoter expression, E. coli promoter expression with transformation efficiency >1 × 10^5 CFU/µg pUC19.
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What are GlycFree (λDE3) Competent Cells?
GlycFree (λDE3) competent cells are optimized E. coli host cells developed for high-efficiency Expression of non-glycosylated recombinant proteins workflows including Non-glycosylated recombinant protein expression, Sugar-free protein expression, T7 promoter expression, E. coli promoter expression. These cells support reliable plasmid uptake, stable propagation, and reproducible transformation performance for molecular biology and protein engineering applications.
Why Choose This Strain?
- Transformation efficiency: >1 × 10^5 CFU/µg pUC19
- Specialized expression strain
- Supports plasmids up to Standard bacterial expression plasmids
- Stability: Defective in UDP-glucose synthesis to reduce aberrant glycosylation during expression
Key Features
- Strain: GlycFree (λDE3)
- Format: 10 × 0.1 mL/tube
- Cell type: Chemically competent
- Insert compatibility: Expression construct-dependent
- Optimized for Expression of non-glycosylated recombinant proteins
Applications
- Non-glycosylated recombinant protein expression
- Sugar-free protein expression
- T7 promoter expression
- E. coli promoter expression
Workflow Compatibility
- Expression of proteins prone to aberrant glycosylation
- UDPG-defective E. coli expression workflows
- Production of native non-glycosylated protein forms
- Phage P1-resistant strain workflows
Specifications
| Genotype | GlycFree (λDE3), λDE3 lysogen of E. coli M226 strain; UDP-glucose-defective background |
|---|---|
| Antibiotic Resistance | Depends on transformed plasmid |
| Growth Conditions | Standard E. coli expression media with appropriate plasmid antibiotic; product page notes expression in E. coli |
| Plasmid Types | T7 expression vectors, E. coli promoter-driven vectors, pUC19 |
| Recombination Notes | Specialized UDPG-defective expression background; not primarily a reduced-recombination cloning strain |
| Max Plasmid Size | Standard bacterial expression plasmids |
Detailed Specifications
| Stability Type | Defective in UDP-glucose synthesis to reduce aberrant glycosylation during expression |
|---|---|
| Insert Size Compatibility | Expression construct-dependent |
| Format | 10 × 0.1 mL/tube |
Handling & Protocol
| Transformation Method | Heat shock |
|---|---|
| Protocol Time | ~2 hours to plating, plus overnight incubation |
| Recovery Time | Not specified on product page |
| Storage Conditions | -80°C |
| Shipping Conditions | Dry ice |
| Shelf Life | ~6 - 12 months at -80°C (typical competent cell stability) |
Industry Comparison
Comparable to specialized λDE3 expression strains for non-glycosylated protein production for Expression of non-glycosylated recombinant proteins workflows.
Comparable to specialized λDE3 expression strains designed to reduce aberrant glycosylation and support expression of non-glycosylated recombinant proteins in E. coli.
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Quality Control
- Transformation efficiency validated with control plasmid
- Genotype verified
- Contamination-free
- CoA provided
Key Advantages
- Engineered for expression of sugar-free recombinant proteins in E. coli
- Defective in UDP-glucose synthesis
- Helps produce non-glycosylated target proteins in native conformation
- Carries T7 RNA polymerase under IPTG-inducible lacUV5 control
- Resistant to phage P1
Why Researchers Choose Amid Biosciences Competent Cells
- High transformation efficiency for reliable cloning workflows
- Optimized strains for phage display, mutagenesis, and protein engineering
- Stringent quality control testing
- Fast shipping and scientific support
- Research-use-only products manufactured for reproducibility
Related Products
- SS320 Competent Cells for Large Phage Display Libraries
- TG1 Competent Cells for Antibody Phage Display
- DH5α Competent Cells for Routine Cloning
Research Use Only. Not for diagnostic or therapeutic use.