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SHP2 Protein, Human, Recombinant, Biotinylated

SHP2 Protein, Human, Recombinant, Biotinylated

Regular price $ 800.00 USD
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SHP2, a Src homology 2 (SH2) domain containing non-transmembrane protein tyrosine phosphatase (PTP), is involved in a variety of signal transduction processes, such as the Ras-Raf-MAP kinase, Jak-Stat, and PI3 kinase pathways (1). Experimental data have also indicated SHP2 as a direct activator of Ras and a potential therapeutic target for cancers driven by oncogenic or hyperactive Ras variants (2, 3).

Recombinant SHP2 protein with the N-terminal AviTag™ peptide and His-tag is produced in E. coli cells and site-specifically biotinylated at AviTag with BirA enzyme.

Catalog # SHP2-B-301

This product is for laboratory research use only.