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Ral B Protein, Human, Recombinant, Biotinylated | Cancer Research

Amid Biosciences | Protein Engineering Company

RalB Protein, Human, Recombinant, Biotinylated

$ 800.00

Ras-related protein Ral-B (RALB) is a member of the Ras GTPase family and shares a high structural similarity with RAS proteins (1). In human cells, the two protein isoforms, RALA and RALB, have been shown to play roles in the proliferation, survival, and metastasis of a variety of human cancers. RALA and RALB share 81% sequence homology with one another and more than 50% sequence homology with RAS. Given their importance in cancer biology, RAL proteins have emerged as desirable clinical targets (2).

Recombinant RalB protein with the N-terminal AviTag™ peptide and His-tag is produced in E. coli cells and site-specifically biotinylated at AviTag with BirA enzyme (

Tag(s): The N-terminal 8XHis and AviTag
Amino Acids: 1-206 of RalB (UniProt # P112334)

Catalog # RALB-B-301

Storage buffer: 20 mM Tris-HCl, pH 7.5, 100 mM NaCl, 2 mM DTT, 10% Glycerol. 
Molecular weight: ~27 kDa
Purity: >90% by Coomassie staining 
Storage is recommended at -80°C. 

International Shipping:  Product requires shipping on dry ice. Please contact for shipment estimates.

For Bulk Orders or Custom Packaging:  please contact

This product is for laboratory research use only.

1. Yan, C., Theodorescu, D. RAL GTPases: Biology and Potential as Therapeutic Targets in Cancer. Pharmacol Rev. 2018, 70:1–11;

2. Richardson, D. et al. The RAL Enigma: Distinct Roles of RALA and RALB in Cancer. Cells 2022, 11(10), 1645;

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