RalB Protein, Human, Recombinant, Biotinylated

Ras-related protein Ral-B (RALB) is a member of the Ras GTPase family and shares a high structural similarity with RAS proteins (1). In human cells, the two protein isoforms, RALA and RALB, have been shown to play roles in the proliferation, survival, and metastasis of a variety of human cancers. RALA and RALB share 81% sequence homology with one another and more than 50% sequence homology with RAS. Given their importance in cancer biology, RAL proteins have emerged as desirable clinical targets (2).

Recombinant RalB protein with the N-terminal AviTag™ peptide and His-tag is produced in E. coli cells and site-specifically biotinylated at AviTag with BirA enzyme.

Catalog # RALB-B-301

For Research Use Only (RUO). This product is for research use only. It is not intended for diagnostic or therapeutic use in humans or animals.