KRAS G12R Protein Human, Recombinant, Biotinylated at the C-terminus | Amid Biosciences

The recombinant KRAS G12R (1-166) protein biotinylated at the C-terminus is designed for high-confidence binding and interaction studies. This construct supports site-specific biotinylation for surface-based assays.

This mutation is clinically relevant and widely used in oncology and targeted therapy research.

Catalog# KRAS12R-B-C-301

Key Features

• KRAS G12R clinically relevant mutation
• C-terminal AviTag™, C-terminal 6XHis tagged construct
• Supports site-specific biotinylation
• High purity recombinant protein
• Optimized for binding assays
• Research Use Only (RUO)

Applications

• SPR
• BLI
• ELISA
• Pull-down
• AlphaScreen
• MST
• Protein–protein interaction studies
• Drug discovery workflows

Biological Context & Applications

Cancer Indications

Pancreatic ductal adenocarcinoma, colorectal cancer (rare), lung cancer (rare)

Binding Partners

RAF1, PI3K, SOS1, RalGDS

Application Notes

Improved assay reproducibility with oriented immobilization; pathway-specific research;

suitable for biochemical and cell-free assays

For Research Use Only (RUO). This product is for research use only. It is not intended for diagnostic or therapeutic use in humans or animals.