{"title":"Recombinant Proteins","description":"\u003cp\u003eAmid Biosciences uses proprietary expression and purification technology to produce high purity recombinant proteins and enzymes with high yields.\u003c\/p\u003e\n\u003cp\u003eOur protein collection includes Streptavidins, BirA Biotin Ligases, Lambda Protein Phosphatase, HRV 3C Protease, TEV Protease, Saposin A, Saposin B, Saposin C, Saposin D, human STING, and KRAS proteins.\u003c\/p\u003e","products":[{"product_id":"recombinant-streptavidin-his-tag","title":"Streptavidin, Recombinant, His-Tag | High Purity \u0026 Activity","description":"\u003cp data-path-to-node=\"6,0\"\u003e\u003cb data-path-to-node=\"6,0\" data-index-in-node=\"0\"\u003eRecombinant Streptavidin\u003c\/b\u003e is a homo-tetrameric protein variant (core streptavidin, amino acids 13-139) produced in \u003ci data-path-to-node=\"6,0\" data-index-in-node=\"114\"\u003eE. coli\u003c\/i\u003e and purified using proprietary chromatographic techniques. Consisting of a single, non-glycosylated polypeptide chain of 136 amino acids, it includes an \u003cb data-path-to-node=\"6,0\" data-index-in-node=\"275\"\u003eN-terminal His-Tag\u003c\/b\u003e and features a molecular mass of 14.4 kDa (approximately 57.7 kDa per tetramer).\u003c\/p\u003e\n\u003cp data-path-to-node=\"6,1\"\u003eStreptavidin is widely used in molecular biology due to its extraordinarily high affinity for biotin (\u003cspan class=\"math-inline\" data-math=\"\\text{K}_\\text{d} \\approx 10^{-14} \\text{ mol\/L}\" data-index-in-node=\"102\"\u003e$\\text{K}_\\text{d} \\approx 10^{-14} \\text{ mol\/L}$\u003c\/span\u003e). Because it lacks carbohydrate modifications and maintains a near-neutral pI, it yields significantly lower non-specific binding compared to native avidin.\u003c\/p\u003e\n\u003ch3 data-path-to-node=\"6,2\"\u003eKey Features \u0026amp; Applications:\u003c\/h3\u003e\n\u003cul data-path-to-node=\"6,3\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"6,3,0,0\"\u003e\u003cb data-path-to-node=\"6,3,0,0\" data-index-in-node=\"0\"\u003eHigh Affinity \u0026amp; Stability:\u003c\/b\u003e The streptavidin-biotin complex remains exceptionally stable across broad pH and temperature ranges.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"6,3,1,0\"\u003e\u003cb data-path-to-node=\"6,3,1,0\" data-index-in-node=\"0\"\u003eVersatile Workflows:\u003c\/b\u003e Ideal for affinity protein purification, immunoassays, Western blotting, ELISA detection, histochemistry, FISH, and cellular imaging.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"6,3,2,0\"\u003e\u003cb data-path-to-node=\"6,3,2,0\" data-index-in-node=\"0\"\u003eConvenient Tagging:\u003c\/b\u003e Equipped with an N-terminal His-Tag for seamless detection or secondary immobilization.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 data-path-to-node=\"6,4\"\u003eSpecifications:\u003c\/h3\u003e\n\u003cul data-path-to-node=\"6,5\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"6,5,0,0\"\u003e\u003cb data-path-to-node=\"6,5,0,0\" data-index-in-node=\"0\"\u003eActivity:\u003c\/b\u003e Greater than 16 U\/mg (1 unit binds 1 µg of D-biotin).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"6,5,1,0\"\u003e\u003cb data-path-to-node=\"6,5,1,0\" data-index-in-node=\"0\"\u003eStorage Buffer:\u003c\/b\u003e 40 mM Phosphate buffer (pH 7.2), 120 mM NaCl, 0.05% Tween 20, 20% glycerol.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"6,5,2,0\"\u003e\u003cb data-path-to-node=\"6,5,2,0\" data-index-in-node=\"0\"\u003eFormulation Sequence:\u003c\/b\u003e \u003ccode data-path-to-node=\"6,5,2,0\" data-index-in-node=\"22\"\u003eMHHHHHHKLAEAGITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAEARINTQWLLTSGTTEANAWKSTLVGHDTFTKVKPSAAS\u003c\/code\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"6,5,3,0\"\u003e\u003cb data-path-to-node=\"6,5,3,0\" data-index-in-node=\"0\"\u003eCatalog Numbers:\u003c\/b\u003e STR-301-1 (1 mg), STR-301-5 (5 mg), STR-301-25 (25 mg), STR-301-100 (100 mg).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"6,5,4,0\"\u003e\u003cb data-path-to-node=\"6,5,4,0\" data-index-in-node=\"0\"\u003eIntended Use:\u003c\/b\u003e \u003cstrong\u003eFor research use only (RUO).\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Amid Biosciences","offers":[{"title":"5 mg","offer_id":25626904969,"sku":"STR-301-5","price":550.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":59537185931345,"sku":"STR-301-1","price":200.0,"currency_code":"USD","in_stock":true},{"title":"25 mg","offer_id":59537187405905,"sku":"STR-301-25","price":2200.0,"currency_code":"USD","in_stock":true},{"title":"100 mg","offer_id":59537190682705,"sku":"STR-301-100","price":6820.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/Streptavidin_Recombinant_His-Tag_High_Purity_Activity.png?v=1779573023"},{"product_id":"recombinant-bira-biotin-ligase-in-vitro-biotinylation","title":"BirA Biotin Protein Ligase, Recombinant","description":"\u003ch2\u003eRecombinant BirA Biotin Ligase (EC 6.3.4.15)\u003c\/h2\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cspan\u003eBirA (also known as biotin protein ligase or BPL) is widely used for antibody biotinylation, proximity-dependent biotinylation (BioID), and streptavidin\/avidin-based pull-down assays. Because biotinylation is confined to the AviTag sequence (GLNDIFEAQKIEWHE), it avoids the non-specific labeling seen with chemical NHS-ester reagents, preserving protein activity and enabling oriented capture on streptavidin surfaces. \u003cmeta charset=\"utf-8\"\u003eUnlike chemical NHS-ester methods that produce heterogeneous mixtures, BirA achieves site-specific biotinylation exclusively at the AviTag lysine residue.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eKey Features \u0026amp; Specifications:\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSource \u0026amp; Expression:\u003c\/strong\u003e Expressed in \u003cem\u003eE. coli\u003c\/em\u003e cell expression system (amino acids 3–321).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 36.2 kDa.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurification Tag:\u003c\/strong\u003e Features an N-terminal His-tag, allowing for easy removal post-reaction using a Ni-NTA column (if the substrate lacks a His-tag).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e \u0026gt;90% as determined by SDS-PAGE (Coomassie staining).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHigh Activity:\u003c\/strong\u003e 5,000 Units\/µg. (1 Unit biotinylates 1 pmol of AviTag peptide substrate in 30 minutes at 30°C).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eConcentration:\u003c\/strong\u003e 1.0 mg\/mL (by A280).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eApplications:\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eSite-specific \u003cem\u003ein vitro\u003c\/em\u003e biotinylation of target proteins and antibodies.\u003c\/li\u003e\n\u003cli\u003eProximity-dependent biotinylation and cell labeling applications.\u003c\/li\u003e\n\u003cli\u003ePreparation of high-affinity complexes for streptavidin\/avidin pull-downs, immobilization, and functionalization assays.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Amid Biosciences","offers":[{"title":"100 ug","offer_id":12268311478353,"sku":"BBL-301-100","price":240.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/BirA_Biotin_Protein_Ligase_Recombinant.png?v=1779579481"},{"product_id":"high-purity-streptavidin-recombinant","title":"Streptavidin Recombinant | Amid Biosciences","description":"\u003ch3\u003eRecombinant Streptavidin (Core, High Purity \u0026amp; Activity)\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eRecombinant Streptavidin\u003c\/strong\u003e is a homo-tetrameric protein produced in \u003cem\u003eE. coli\u003c\/em\u003e as an N- and C-terminal shortened variant (\u003cstrong\u003ecore streptavidin\u003c\/strong\u003e, amino acids 13–139). It is purified using proprietary chromatographic techniques to ensure maximum purity and excellent activity.\u003c\/p\u003e\n\u003cp\u003eBecause it lacks carbohydrate modifications and has a near-neutral isoelectric point (pI), our recombinant streptavidin offers significantly lower non-specific binding compared to native avidin, making it ideal for sensitive molecular biology applications.\u003c\/p\u003e\n\n\u003ch3\u003eKey Features \u0026amp; Specifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHigh Affinity:\u003c\/strong\u003e Binds D-biotin with a dissociation constant (Kd) of ~1.0 x 10^-14 mol\/L, one of the strongest non-covalent interactions in nature.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eExceptional Stability:\u003c\/strong\u003e The streptavidin-biotin complex remains stable across a wide range of temperatures and pH levels.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eHigh Activity:\u003c\/strong\u003e Greater than 16 U\/mg (1 unit binds 1 µg of D-biotin).\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Supplied as a 5 mg\/mL solution in 0.5X PBS buffer (pH 7.4) and 50% glycerol.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 13.4 kDa per monomer (single, non-glycosylated polypeptide chain of 128 amino acids); approximately 53.6 kDa per functional tetramer.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eApplications\u003c\/h3\u003e\n\u003cp\u003eOptimized for use in high-performance downstream research applications, including:\u003c\/p\u003e\n\u003cul\u003e\n  \u003cli\u003eEnzyme-Linked Immunosorbent Assays (\u003cem\u003eELISA detection\u003c\/em\u003e)\u003c\/li\u003e\n  \u003cli\u003eFlow Cytometry and Immunohistochemistry\u003c\/li\u003e\n  \u003cli\u003eWestern Blotting and Protein Purification\u003c\/li\u003e\n  \u003cli\u003eFISH (Fluorescence In Situ Hybridization) and Microarrays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003e\u003cem\u003eCatalog # ST-302-5 (5 mg), ST-302-25 (25 mg).\u003c\/em\u003e\u003cbr\u003e\n\u003cstrong\u003eThis product is for research use only (RUO).\u003c\/strong\u003e\u003c\/p\u003e","brand":"Amid Biosciences","offers":[{"title":"5 mg","offer_id":2019419783177,"sku":"ST-302-5","price":550.0,"currency_code":"USD","in_stock":true},{"title":"25 mg","offer_id":59537145856081,"sku":"ST-302-25","price":2200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/Streptavidin_Recombinant_High_Purity.png?v=1779758165"},{"product_id":"recombinant-his-tag-tev-protease","title":"TEV Protease, Recombinant, His-Tag | Affinity Tag Removal","description":"\u003ch2\u003eHigh-Specificity Recombinant TEV Protease for Fusion Protein Cleavage\u003c\/h2\u003e\n\u003cp\u003eAmid Biosciences' \u003cstrong\u003eTEV Protease\u003c\/strong\u003e is a highly purified, 27 kDa engineered form of the \u003cem\u003eTobacco Etch Virus (TEV) protease\u003c\/em\u003e. It recognizes the stringent seven-amino-acid sequence \u003cstrong\u003eGlu-Asn-Leu-Tyr-Phe-Gln-(Gly\/Ser) [ENLYFQ(G\/S)]\u003c\/strong\u003e, cleaving highly specifically between the Gln and Gly\/Ser residues with minimal off-target effects.\u003c\/p\u003e\n\u003cp\u003eEquipped with an \u003cstrong\u003eN-terminal His-tag\u003c\/strong\u003e, this recombinant enzyme can be effortlessly removed from your cleavage reaction using standard Immobilized Metal Affinity Chromatography (IMAC), making it an ideal choice for downstream affinity tag removal after protein purification.\u003c\/p\u003e\n\u003ch3\u003eKey Features \u0026amp; Benefits\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHigh Specificity:\u003c\/strong\u003e Rigorously selective cleavage activity with virtually no non-specific proteolysis.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBroad Operating Window:\u003c\/strong\u003e Highly active over a wide temperature range (+4°C to 30°C) and pH range (6.0 to 8.5). Optimal cleavage occurs at 30°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVersatile Application:\u003c\/strong\u003e Fully compatible with both standard in-solution and on-column cleavage protocols.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePremium Purity:\u003c\/strong\u003e Purified from \u003cem\u003eE. coli\u003c\/em\u003e via proprietary chromatographic techniques; verified at \u0026gt;90% pure via SDS-PAGE visualization.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eProduct Specifications \u0026amp; Components \u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSource:\u003c\/strong\u003e \u003cem\u003eE. coli\u003c\/em\u003e expression system\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eActivity \u0026amp; Concentration:\u003c\/strong\u003e 10,000 U\/ml (~10,000 U\/mg)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUnit Definition:\u003c\/strong\u003e One unit of TEV Protease cleaves ≥85% of 3 µg control substrate in 1 hour at 30°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSupplied Reagents:\u003c\/strong\u003e Includes 1 vial of 20X TEV buffer (1 M Tris-HCl (pH 8.0), 10 mM EDTA) and 1 vial of 100 mM DTT.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage Conditions:\u003c\/strong\u003e Store strictly at -20°C.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eCatalog # TVP-301-1\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e(1000 Units),\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eTVP-301-5\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e(5000 Units).\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eThis product is intended for laboratory research use only.\u003c\/strong\u003e International shipping requires ice packs.\u003c\/em\u003e\u003c\/p\u003e","brand":"Amid Biosciences| Competent Cells and Protein Expression Vectors","offers":[{"title":"1000 Units","offer_id":12205462814801,"sku":"TVP-301-1","price":90.0,"currency_code":"USD","in_stock":true},{"title":"5000 Units","offer_id":59537207787601,"sku":"TVP-301-5","price":400.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/TEV_Protease_Recombinant_His-Tag_Affinity_Tag_Removal.png?v=1736368196"},{"product_id":"lambda-protein-phosphatase-high-dephosphorylation-activity","title":"Lambda Protein Phosphatase for Dephosphorylation of Proteins","description":"\u003cp\u003e\u003cstrong\u003eLambda Protein Phosphatase (Lambda PP)\u003c\/strong\u003e is a Mn2+-dependent protein phosphatase with \u003cstrong\u003eactivity towards phosphorylated serine, threonine and tyrosine\u003c\/strong\u003e residues (1, 2). It is the 221 amino-acid product of the ORF221 open reading frame on bacteriophage lambda (1). The enzyme is inhibited by vanadate ions and can be heat inactivated at 65¡ C for 1 hour in the presence of 50 mM Na\u003csub\u003e2\u003c\/sub\u003eEDTA (3).\u003c\/p\u003e","brand":"Amid Biosciences| Competent Cells and Protein Expression Vectors","offers":[{"title":"20,000 Units","offer_id":12262441844817,"sku":"LPP-301-20","price":120.0,"currency_code":"USD","in_stock":true},{"title":"100,000 Units","offer_id":59537079337041,"sku":"LPP-301-100","price":500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/Lambda_Protein_Phosphatase_for_Dephosphorylation_of_Proteins.png?v=1736368779"},{"product_id":"recombinant-human-saposin-a-protein","title":"Saposin A, Human, Recombinant","description":"\u003cp\u003e\u003cstrong\u003eSaposin A\u003c\/strong\u003e is a small, highly stable, cysteine-rich alpha-helical glycoprotein localized within the lysosomal compartment. Derived from the prosaposin precursor protein, it serves as an essential non-enzymatic cofactor required for the lysosomal degradation of galactosylceramide by β-galactosylceramidase. While native saposins are glycosylated, non-glycosylated recombinant saposins retain their full biological activation properties in functional \u003cem\u003ein vitro\u003c\/em\u003e assays, making them exceptional tools for membrane biophysics.\u003c\/p\u003e\n\u003ch3\u003eKey Applications: Lipid Nanoparticle Scaffolding\u003c\/h3\u003e\n\u003cp\u003eBeyond its native role in sphingolipid catabolism, recombinant Saposin A is widely utilized as a scaffolding protein in versatile lipid nanoparticle systems (saposin-lipoprotein discs). These engineered scaffolds allow researchers to reconstitute challenging membrane proteins and transporters into a native-like lipid bilayer. This technology is highly valued across structural biology (including cryo-EM determination), targeted therapeutic delivery of protein-based pharmacological agents, and vaccine adjuvant formulation.\u003c\/p\u003e\n\u003ch3\u003eProduct Features \u0026amp; Specifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eExpression Host:\u003c\/strong\u003e Produced in an optimized \u003cem\u003eEscherichia coli\u003c\/em\u003e (\u003cem\u003eE. coli\u003c\/em\u003e) bacterial expression system.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTag Status:\u003c\/strong\u003e Expressed as an N-terminal His-tag fusion and purified using proprietary chromatography steps, followed by site-specific proteolytic cleavage to yield a completely \u003cstrong\u003etag-free\u003c\/strong\u003e final protein.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHigh Purity:\u003c\/strong\u003e Verified at \u0026gt;90% purity by Coomassie blue staining on SDS-PAGE.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation \u0026amp; Concentration:\u003c\/strong\u003e Supplied at 1.0 – 2.0 mg\/mL in 50 mM Tris-HCl, pH 7.5, 50 mM NaCl, and 50% Glycerol for premium stability.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003e\u003cem\u003eCatalog Number: SAPA-301 | \u003cstrong\u003eThis product is intended for laboratory research use only (RUO)\u003c\/strong\u003e. Shipping on ice packs required. \u003c\/em\u003e\u003c\/small\u003e\u003c\/p\u003e","brand":"Amid Biosciences","offers":[{"title":"0.1 mg","offer_id":12475835154513,"sku":"SAPA-301-1","price":600.0,"currency_code":"USD","in_stock":true},{"title":"1.0 mg","offer_id":59537114955857,"sku":"SAPA-301-2","price":2800.0,"currency_code":"USD","in_stock":true},{"title":"10.0 mg","offer_id":59537117184081,"sku":"SAPA-301-10","price":7500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/Saposin_A_Human_Recombinant.png?v=1779503974"},{"product_id":"saposin-c-human-recombinant-his-tag","title":"Saposin C, Human, Recombinant, His-tag","description":"\u003cp\u003e\u003cstrong\u003eSaposin C\u003c\/strong\u003e (SAP-C) is a small, heat-stable lysosomal glycoprotein derived from the prosaposin precursor protein via site-specific proteolytic cleavage. Among the four prosaposin-derived domains, Saposin C shares the highest structural and sequence homology with Saposin A. It acts as an indispensable biological cofactor required for the lysosomal activation of β-glucocerebrosidase (GBA), the enzyme deficient in Gaucher disease. Additionally, Saposin C plays a critical role in cellular immunology by facilitating the presentation of lipid antigens through CD1b molecules to human T cells. While native lysosomal saposins are heavily glycosylated, non-glycosylated recombinant variants expressed in bacterial systems maintain full biological activation properties in functional \u003cem\u003ein vitro\u003c\/em\u003e biochemical assays.\u003c\/p\u003e\n\u003ch3\u003eProduct Features \u0026amp; Specifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eExpression System:\u003c\/strong\u003e Engineered and expressed in an optimized \u003cem\u003eEscherichia coli\u003c\/em\u003e (\u003cem\u003eE. coli\u003c\/em\u003e) bacterial host.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFusion Tag:\u003c\/strong\u003e Features a C-terminal Polyhistidine (6xHis) tag to allow robust detection, tracking, and oriented immobilization.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHigh Purity:\u003c\/strong\u003e Verified at \u0026gt;90% purity by Coomassie blue staining on SDS-PAGE.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation \u0026amp; Concentration:\u003c\/strong\u003e Supplied at a concentration of 1.0 mg\/mL (determined by A280) in 10 mM Tris-HCl, pH 7.5, 100 mM NaCl, and 50% Glycerol for premium structural stability.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eValidated Assay Applications\u003c\/h3\u003e\n\u003cp\u003eThis recombinant human Saposin C construct is specifically optimized for lysosomal enzyme activity assays, \u003cem\u003ein vitro\u003c\/em\u003e glucocerebrosidase reconstitution kinetics, lipid-binding biophysical studies, CD1b lipid antigen presentation assays, Surface Plasmon Resonance (SPR), and Bio-Layer Interferometry (BLI).\u003c\/p\u003e\n\u003cp\u003e\u003csmall\u003e\u003cem\u003eCatalog Numbers: SAPC-301-1 (0.1 mg) | SAPC-301-2 (1.0 mg). \u003cstrong\u003eThis product is intended for laboratory research use only (RUO).\u003c\/strong\u003e It is not intended for diagnostic or therapeutic use in humans or animals. \u003c\/em\u003e\u003c\/small\u003e\u003c\/p\u003e","brand":"Amid Biosciences","offers":[{"title":"0.1 mg","offer_id":12475963768913,"sku":"SAPC-301-1","price":600.0,"currency_code":"USD","in_stock":true},{"title":"1.0 mg","offer_id":59537121280081,"sku":"SAPC-301-2","price":2800.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/Saposin_C_Human_Recombinant_His-tag.png?v=1779505009"},{"product_id":"recombinant-human-kras-protein-avitag","title":"Wild Type KRAS Protein, Human, Recombinant, AviTag","description":"\u003cp\u003eHuman KRAS protein is a small guanosine triphosphatase (GTPase) that is the component of the mitogen activated protein kinase (MAPK) signaling pathway. High occurrences of KRAS mutations in some types of cancers make KRAS one of the most important targets in oncology for drug development.\u003c\/p\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"0.1 mg","offer_id":31944706261073,"sku":"KRAS-301-1","price":500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/Wild_Type_KRAS_Protein_Human_Recombinant_AviTag.png?v=1736453657"},{"product_id":"kras-g12c-protein-human-recombinant-avitag","title":"KRAS G12C Protein, Human, Recombinant, AviTag","description":"\u003cp\u003eHuman KRAS protein is a small guanosine triphosphatase (GTPase) that is the component of the mitogen activated protein kinase (MAPK) signaling pathway. High occurrences of KRAS mutations in some types of cancers makeÊKRASÊone of the most important targets in oncology for drug development.Ê\u003cspan\u003eÊT\u003c\/span\u003e\u003cspan\u003ehe four most frequent KRAS mutations areÊ\u003c\/span\u003e\u003cspan\u003eG12D, G12V, G13D, and G12C.\u003c\/span\u003e\u003cspan\u003eÊ\u003c\/span\u003e\u003cspan\u003eÊ\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"0.1 mg","offer_id":31944897560657,"sku":"KRAS12C-301","price":500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/KRAS_G12C_Protein_Human_Recombinant_AviTag.png?v=1736453897"},{"product_id":"kras-g12d-protein-human-recombinant-avitag","title":"KRAS G12D Protein, Human, Recombinant, AviTag","description":"\u003cp\u003eHuman KRAS protein is a small guanosine triphosphatase (GTPase) that is the component of the mitogen activated protein kinase (MAPK) signaling pathway. High occurrences of KRAS mutations in some types of cancers makeÊKRASÊone of the most important targets in oncology for drug development.\u003c\/p\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"0.1 mg","offer_id":31944909848657,"sku":"KRAS12D-301","price":500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/KRAS_G12D_Protein_Human_Recombinant_AviTag.png?v=1736453577"},{"product_id":"kras-g12d-protein-human-recombinant-biotinylated","title":"KRAS G12D Protein, Human, Recombinant, Biotinylated","description":"\u003cp\u003eRecombinant \u003cstrong\u003eKRAS G12D \u003c\/strong\u003eprotein with the N-terminal AviTag\u003cmeta charset=\"utf-8\"\u003e\u003cb data-index-in-node=\"18\" data-path-to-node=\"6,0,0\"\u003e™\u003c\/b\u003e peptide and His-tag is produced in \u003cem\u003eE. coli\u003c\/em\u003e cells and site-specifically biotinylated at AviTag with \u003ca rel=\"noopener\" title=\"BirA Biotin Ligase | In-vitro Biotinylation | Site-specific | High Activity\" href=\"https:\/\/amidbiosciences.com\/products\/bira-biotin-ligase-in-vitro-biotinylation\" target=\"_blank\"\u003eBirA enzyme. \u003c\/a\u003e\u003c\/p\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"0.1 mg","offer_id":32374587588689,"sku":"KRAS12D-B-301-01","price":800.0,"currency_code":"USD","in_stock":true},{"title":"1.0 mg","offer_id":59460791205969,"sku":"KRAS12D-B-301-1","price":6000.0,"currency_code":"USD","in_stock":true},{"title":"0.05 mg","offer_id":59460791238737,"sku":"KRAS12D-B-301-005","price":500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/KRAS_G12D_Protein_Human_Recombinant_Biotinylated.png?v=1736453375"},{"product_id":"kras-g12c-protein-human-recombinant-biotinylated","title":"KRAS G12C Protein, Human, Recombinant, Biotinylated | Amid Bio","description":"\u003cp\u003eRecombinant \u003cstrong\u003eKRAS G12C \u003c\/strong\u003eprotein with N-terminal AviTag\u003cmeta charset=\"utf-8\"\u003e™ and His-tag is produced in \u003cem\u003eE. coli \u003c\/em\u003ecells and site-specifically biotinylated at the AviTag with \u003ca href=\"https:\/\/amidbiosciences.com\/products\/bira-biotin-ligase-in-vitro-biotinylation\" title=\"BirA Biotin Ligase | In-vitro Biotinylation | Site-specific | High Activity\" rel=\"noopener\" target=\"_blank\"\u003eBirA enzyme\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eFor Research Use Only (RUO).\u003c\/strong\u003e\u003cspan\u003e This product is for research use only. It is not intended for diagnostic or therapeutic use in humans or animals. \u003c\/span\u003e\u003c\/p\u003e","brand":"Amid Biosciences","offers":[{"title":"0.05 mg","offer_id":39531486117969,"sku":"KRAS12C-B-301-005","price":500.0,"currency_code":"USD","in_stock":true},{"title":"0.1 mg","offer_id":59460791074897,"sku":"KRAS12C-B-301-01","price":800.0,"currency_code":"USD","in_stock":true},{"title":"1.00 mg","offer_id":59460791107665,"sku":"KRAS12C-B-301-1","price":6000.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/KRAS_G12C_Protein_Human_Recombinant_Biotinylated.png?v=1736455145"},{"product_id":"kras-g13d-protein-human-recombinant-avitag","title":"KRAS G13D Protein, Human, Recombinant, AviTag","description":"\u003cp\u003eHuman KRAS protein is a small guanosine triphosphatase (GTPase) that is the component of the mitogen activated protein kinase (MAPK) signaling pathway. High occurrences of KRAS mutations in some types of cancers makeÊKRASÊone of the most important targets in oncology for drug development. The four most frequent KRAS mutations areÊ\u003cspan\u003eG12D, G12V, G13D, and G12C.\u003c\/span\u003e\u003c\/p\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"0.1 mg","offer_id":32395727470673,"sku":"KRAS13D-301","price":500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/KRAS_G13D_Protein_Human_Recombinant_AviTag.png?v=1736454887"},{"product_id":"kras-g12v-protein-human-recombinant-avitag","title":"KRAS G12V Protein, Human, Recombinant, AviTag","description":"\u003cp\u003eHuman KRAS protein is a small guanosine triphosphatase (GTPase) that is the component of the mitogen activated protein kinase (MAPK) signaling pathway. High occurrences of KRAS mutations in some types of cancers makeÊKRASÊone of the most important targets in oncology for drug development.\u003c\/p\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"0.1 mg","offer_id":32395782651985,"sku":"KRAS12V-301","price":500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/KRAS_G12V_Protein_Human_Recombinant_AviTag.png?v=1736454199"},{"product_id":"recombinant-human-saposin-b-protein","title":"Saposin B, Human, Recombinant","description":"\u003cp\u003e\u003cstrong\u003eSaposin B\u003c\/strong\u003e (SAP-B) is a small, non-enzymatic glycosphingolipid activator protein essential for the lysosomal degradation of cerebroside sulfates (sulfatides). It functions as a biological detergent, physically extracting target lipid molecules from biological membranes to form a soluble, transportable protein-lipid complex. This presentation renders the substrate accessible to the hydrolytic enzyme arylsulfatase A (ARSA). Deficiencies or genetic mutations in the prosaposin gene leading to a loss of functional Saposin B result in Saposin B deficiency, a rare lysosomal storage disease phenotypically resembling metachromatic leukodystrophy (MLD).\u003c\/p\u003e\n\u003ch3\u003eKey Research \u0026amp; Assay Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eEnzyme Replacement \u0026amp; Activity Assays:\u003c\/strong\u003e Ideal as a functional cofactor for reconstituting \u003cem\u003ein vitro\u003c\/em\u003e arylsulfatase A degradation kinetics and lipid editing mechanics.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmunology \u0026amp; NKT Cell Activation:\u003c\/strong\u003e Used in downstream investigations profiling phospholipid transfer dynamics and lipid antigen presentation to Natural Killer T (NKT) cells.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDrug Discovery Support:\u003c\/strong\u003e High-value target component for screening therapeutics, small molecules, or chaperone designs aiming to mitigate metachromatic leukodystrophy pathways.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eProduct Features \u0026amp; Specifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eExpression System:\u003c\/strong\u003e Engineered and produced in an optimized \u003cem\u003eEscherichia coli\u003c\/em\u003e (\u003cem\u003eE. coli\u003c\/em\u003e) bacterial expression platform.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTag Status:\u003c\/strong\u003e Expressed as an N-terminal His-tag fusion and purified using proprietary chromatography steps, followed by site-specific proteolytic cleavage to yield a completely \u003cstrong\u003etag-free\u003c\/strong\u003e final protein.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence Profile:\u003c\/strong\u003e Comprises the native 79-amino acid mature Saposin B sequence (GDVCQDCIQM...CDE).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHigh Purity:\u003c\/strong\u003e Formulated to \u0026gt;90% purity as verified by Coomassie blue staining on SDS-PAGE.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBuffer Formulation:\u003c\/strong\u003e Supplied at a concentration of 0.5 – 2.0 mg\/mL in 25 mM Phosphate Buffer, pH 7.2, 75 mM NaCl, and 50% Glycerol for premium structural stability.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003e\u003cem\u003eCatalog Number: SAPB-301 | \u003cstrong\u003eThis product is intended for laboratory research use only (RUO)\u003c\/strong\u003e. Long-term storage is recommended at -20°C. \u003c\/em\u003e\u003c\/small\u003e\u003c\/p\u003e","brand":"Amid Biosciences","offers":[{"title":"0.1 mg","offer_id":32396239110225,"sku":"SAPB-301-1","price":600.0,"currency_code":"USD","in_stock":true},{"title":"1.0 mg","offer_id":59537119248465,"sku":null,"price":2800.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/Saposin_B_Human_Recombinant.png?v=1779504561"},{"product_id":"bira-biotin-ligase-mbp-tag-recombinant","title":"BirA Biotin Ligase, MBP-tag, Recombinant","description":"\u003ch3\u003eHigh-Purity Recombinant BirA Biotin Ligase for Site-Specific Labeling\u003c\/h3\u003e\n\u003cp\u003eAmid Biosciences presents high-purity \u003cstrong\u003erecombinant BirA Biotin Ligase\u003c\/strong\u003e (~78 kDa), expressed as a maltose-binding protein (MBP) fusion in \u003cem\u003eE. coli\u003c\/em\u003e cells. This versatile enzyme is engineered with a \u003cstrong\u003edual 6xHis-MBP tag at the N-terminus\u003c\/strong\u003e, enhancing protein solubility and allowing for effortless purification or removal post-biotinylation using Ni-NTA or amylose resin columns.\u003c\/p\u003e\n\u003ch3\u003eKey Applications \u0026amp; Performance\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrecise Site-Specific Biotinylation:\u003c\/strong\u003e Ideal for highly efficient, targeted biotin labeling of proteins and peptides containing an AviTag™ or identical peptide substrate.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVersatile Workflows:\u003c\/strong\u003e Optimized for both rigorous \u003cem\u003ein vitro\u003c\/em\u003e enzymatic labeling and \u003cem\u003ein vivo\u003c\/em\u003e proximity labeling applications.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHigh Specific Activity:\u003c\/strong\u003e Offers robust performance with \u0026gt;3,000 Units\/µg, ensuring reliable results for your molecular biology and assay development needs.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cstrong\u003eCatalog # MBBL-301\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eThis product is intended for research use only (RUO).\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e","brand":"Amid Biosciences","offers":[{"title":"0.1 mg","offer_id":32399019016273,"sku":"MBBL-301","price":370.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/BirA_Biotin_Ligase_MBP-tag_Recombinant.png?v=1779731291"},{"product_id":"sting-protein-human-h232-variant-recombinant","title":"Recombinant Human STING Protein (H232 Variant) for Research Applications | Amid Biosciences","description":"\u003cp data-path-to-node=\"5\"\u003eThis high-purity, recombinant human STING (Stimulator of Interferon Genes) protein represents the H232 variant, the most prevalent allele in the human population. This product is engineered for high-performance use in biochemical assays, structural biology, and the study of innate immune signaling pathways in a laboratory setting.\u003c\/p\u003e\n\u003cp data-path-to-node=\"6\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"6\"\u003eKey Features \u0026amp; Technical Specifications:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"7\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"7,0,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"7,0,0\"\u003eVariant Specificity:\u003c\/b\u003e Contains the H232 (His232) polymorphism, essential for studying natural variations in the STING signaling pathway.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"7,1,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"7,1,0\"\u003eHigh Purity \u0026amp; Activity:\u003c\/b\u003e Purified to \u0026gt;95% via affinity chromatography, ensuring consistent results in ligand-binding studies and enzymatic assays.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"7,2,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"7,2,0\"\u003eResearch Utility:\u003c\/b\u003e Optimized for in-vitro analysis of cGAMP interactions and the characterization of downstream signaling cascades.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"7,3,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"7,3,0\"\u003eFlexible Format:\u003c\/b\u003e Available in multiple concentrations (including 0.1 mg and 1.0 mg) to support both small-scale screening and large-scale structural studies.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"7,4,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"7,4,0\"\u003eStrictly for Research Use:\u003c\/b\u003e This product is intended for laboratory research and development only. It is not for human or animal diagnostic or therapeutic use. \u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"0.1 mg","offer_id":32458064068689,"sku":"STGH-301-1","price":450.0,"currency_code":"USD","in_stock":true},{"title":"1.0 mg","offer_id":59537167908945,"sku":"STGH-301-10","price":2000.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/STING-Protein-Human-H232-variant-Recombinant.png?v=1780450452"},{"product_id":"sting-protein-human-r232-variant-recombinant","title":"STING Protein, Human Recombinant (R232) | Amid Biosciences","description":"\u003cp dir=\"ltr\"\u003e\u003cspan\u003eThis high-purity recombinant human STING (Stimulator of Interferon Genes) protein features the R232 (Arg232) variant, a key polymorphism used in the study of innate immune responses. This product is specifically developed for researchers performing biochemical characterization, protein-protein interaction studies, and structural analysis in a laboratory environment. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eKey Technical Specifications:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003e\u003cstrong\u003eVariant Specificity:\u003c\/strong\u003e\u003cspan\u003e\u003cstrong\u003e \u003c\/strong\u003eContains the R232 polymorphism (Arg232), a critical variant for comparative studies against the H232 allele.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003e\u003cstrong\u003eHigh-Level Purity:\u003c\/strong\u003e\u003cspan\u003e\u003cstrong\u003e \u003c\/strong\u003ePurified via advanced affinity chromatography to ensure \u0026gt;95% purity, providing reliable and reproducible results in enzymatic and binding assays.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003e\u003cstrong\u003eApplication Versatility:\u003c\/strong\u003e\u003cspan\u003e Optimized for in-vitro use, including cGAMP binding studies, interferon signaling research, and the development of innate immunity assays.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003e\u003cstrong\u003eResearch Grade:\u003c\/strong\u003e\u003cspan\u003e\u003cstrong\u003e \u003c\/strong\u003eProvided in a stable, buffered solution designed to maintain protein integrity through multiple freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003e\u003cstrong\u003eStrictly for Research Use:\u003c\/strong\u003e\u003cspan\u003e This product is intended for in-vitro laboratory research and development only. It is not for human or animal diagnostic or therapeutic use.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-path-to-node=\"4\"\u003e\u003cstrong style=\"font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 0.875rem;\"\u003e\u003cb id=\"docs-internal-guid-007d9631-7fff-ccfa-b574-44b9738df7c0\"\u003e\u003c\/b\u003eCatalog #\u003c\/strong\u003e\u003cspan style=\"font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 0.875rem;\"\u003e \u003c\/span\u003e\u003cstrong style=\"font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 0.875rem;\"\u003eSTGR-301 \u003c\/strong\u003e\u003c\/p\u003e","brand":"Amid Biosciences","offers":[{"title":"0.1 mg","offer_id":32458080714833,"sku":"STGR-301-1","price":450.0,"currency_code":"USD","in_stock":true},{"title":"1.0 mg","offer_id":59537173971025,"sku":"STGR-301-10","price":2000.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/Recombinant_Human_STING_Protein_R232_Variant_Signal_Transduction_Research.png?v=1778202027"},{"product_id":"kras-protein-human-recombinant-biotinylated","title":"Wild Type KRAS Protein, Human, Recombinant, Biotinylated","description":"\u003cp data-mce-fragment=\"1\"\u003eRecombinant \u003cstrong data-mce-fragment=\"1\"\u003eKRAS \u003c\/strong\u003eprotein with the N-terminal AviTagª peptide and His-tag is produced in \u003cem data-mce-fragment=\"1\"\u003eE. coli\u003c\/em\u003e cells and site-specifically biotinylated at AviTag with \u003ca href=\"https:\/\/amidbiosciences.com\/products\/bira-biotin-ligase-in-vitro-biotynilation\" title=\"BirA Biotin Ligase | In-vitro Biotinylation | Site-specific | High Activity\" rel=\"noopener\" target=\"_blank\"\u003eBirA enzyme\u003c\/a\u003e.\u003c\/p\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"0.05 mg","offer_id":39531488903249,"sku":"KRAS-301-B-005","price":500.0,"currency_code":"USD","in_stock":true},{"title":"0.1 mg","offer_id":59460791009361,"sku":"KRAS-301-B-01","price":800.0,"currency_code":"USD","in_stock":true},{"title":"1.0 mg","offer_id":59460791042129,"sku":"KRAS-301-B-1","price":6000.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/Wild_Type_KRAS_Protein_Human_Recombinant_Biotinylated.png?v=1736453028"},{"product_id":"biotinylated-human-tl1a-protein-recombinant","title":"TL1A Protein, Human, Recombinant, Biotinylated","description":"\u003cp\u003e\u003cstrong\u003eTL1A\u003c\/strong\u003e, also known as \u003cstrong\u003eTNFSF15\u003c\/strong\u003e, is a tumor necrosis factor (TNF) family member cytokine predominantly expressed by monocytes, macrophages, dendritic cells (DCs), synovial fibroblasts, and endothelial cells. Its cognate cell surface receptor, DR3 (TNFRSF25), is primarily expressed on T cells, where TL1A signaling co-stimulates T-cell activation and drives pro-inflammatory cytokine production. Dysregulation of the TL1A\/DR3 pathway is strongly linked to human inflammatory bowel disease (IBD), Crohn's disease, and various autoimmune pathologies, making it a high-value target for therapeutic antibody screening and biomarker validation.\u003c\/p\u003e\n\n\u003ch3\u003eProduct Features \u0026amp; Specifications\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\n\u003cstrong\u003eExpression System:\u003c\/strong\u003e Engineered and expressed in an optimized \u003cem\u003eE. coli\u003c\/em\u003e bacterial system.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eConstruct Design:\u003c\/strong\u003e Features a DNA sequence encoding human TL1A (Gln58-Leu251) fused with an N-terminal Polyhistidine (His) tag and an AviTag™ peptide sequence.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003ePrecision Biotinylation:\u003c\/strong\u003e Enzymatically biotinylated at the unique AviTag™ site, ensuring uniform molecular orientation and maximum ligand binding capacity.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eNative Conformation:\u003c\/strong\u003e Size-exclusion chromatography (SEC) data confirms that the purified recombinant protein elutes as a fully functional homogenous trimer.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eHigh Purity:\u003c\/strong\u003e Verified at \u0026gt;90% purity by Coomassie blue staining on SDS-PAGE under reducing conditions.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eValidated Assay Applications\u003c\/h3\u003e\n\u003cp\u003eThis biotinylated human TL1A protein is specifically optimized for high-sensitivity binding assays, surface plasmon resonance (SPR), bio-layer interferometry (BLI), AlphaLISA, and ELISA-based high-throughput screening of neutralizing anti-TL1A antibodies.\u003c\/p\u003e\n\n\u003cp\u003e\u003csmall\u003e\u003cem\u003eCatalog Number: TL1A-B-301 | This product is intended for research use only.\u003c\/em\u003e\u003c\/small\u003e\u003c\/p\u003e ","brand":"Amid Biosciences","offers":[{"title":"0.1 mg","offer_id":39301355012177,"sku":"TL1A-B-301-1","price":600.0,"currency_code":"USD","in_stock":true},{"title":"1.0 mg","offer_id":59537201889361,"sku":"TL1A-B-301-2","price":3600.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/products\/TL1A_Protein_Human_Recombinant_Biotinylated.jpg?v=1779483049"},{"product_id":"kras-q61h-protein-human-recombinant-avitag","title":"KRAS Q61H Protein, Human, Recombinant, AviTag","description":"\u003cp style=\"background: white; margin: 0in 0in 11.25pt 0in;\" data-mce-fragment=\"1\"\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; color: #080707;\" data-mce-fragment=\"1\"\u003eRecombinant \u003cstrong style=\"box-sizing: border-box;\" data-mce-fragment=\"1\"\u003e\u003cspan style=\"font-family: 'Arial',sans-serif;\" data-mce-fragment=\"1\"\u003eKRAS Q61H \u003c\/span\u003e\u003c\/strong\u003e\u003c\/span\u003eprotein with the N-terminal AviTag peptide and His-tag is produced in \u003cem style=\"box-sizing: border-box;\" data-mce-fragment=\"1\"\u003e\u003cspan style=\"font-family: 'Arial',sans-serif;\" data-mce-fragment=\"1\"\u003eE. coli\u003c\/span\u003e\u003c\/em\u003e cells. Presence of AviTag peptide is useful for a site-specific biotinylation with \u003ca href=\"https:\/\/amidbiosciences.com\/products\/bira-biotin-ligase-in-vitro-biotynilation\" title=\"BirA Biotin Ligase | In-vitro Biotinylation | Site-specific | High Activity\" rel=\"noopener\" target=\"_blank\"\u003eBirA enzyme\u003c\/a\u003e. \u003c\/p\u003e","brand":"Amid Biosciences","offers":[{"title":"0.1 mg","offer_id":39336321024081,"sku":"KRAS61H-301","price":500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/KRAS_Q61H_Protein_Human_Recombinant_AviTag.png?v=1736454786"},{"product_id":"kras-q61h-protein-human-recombinant-biotinylated","title":"KRAS Q61H Protein, Human, Recombinant Biotinylated | Amid Biosciences","description":"\u003cp\u003eOur recombinant Q61H protein is produced with a dual-tag system (\u003cstrong\u003eHis-Tag and AviTag™\u003c\/strong\u003e) to ensure maximum flexibility in the lab. The site-specific biotinylation provides a uniform orientation on streptavidin surfaces, which is critical for maintaining the accessibility of the mutated switch II region during high-throughput screening (\u003cstrong\u003eHTS\u003c\/strong\u003e) using \u003cstrong\u003eAlphaLISA \u003c\/strong\u003eor \u003cstrong\u003eTR-FRET\u003c\/strong\u003eassays. It also allows to study high-affinity binding to RAF1, PI3K, and RAL GDS via \u003cstrong\u003eSPR (Biacore)\u003c\/strong\u003e or \u003cstrong\u003eBLI (Octet)\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003eAvailable in 0.1 mg and \u003cstrong\u003e1.0 mg bulk packaging \u003c\/strong\u003efor scalable assay development.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCatalog # KRAS61H-B-301\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThis product is for laboratory research use only. \u003c\/strong\u003e\u003c\/p\u003e","brand":"Amid Biosciences","offers":[{"title":"0.1 mg","offer_id":39336330592337,"sku":"KRAS61H-B-301","price":800.0,"currency_code":"USD","in_stock":true},{"title":"1.0 mg","offer_id":59460790878289,"sku":"KRAS61H-B-301-2","price":6000.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/KRAS_Q61H_Protein_Human_Recombinant_Biotinylated.png?v=1736454129"},{"product_id":"kras-g12v-protein-human-recombinant-biotinylated","title":"KRAS G12V Protein, Human, Recombinant, Biotinylated | Amid Biosciences","description":"\u003cp\u003eRecombinant \u003cstrong\u003eKRAS G12V \u003c\/strong\u003eprotein\u003cstrong\u003e \u003c\/strong\u003ewith the N-terminal AviTag™ peptide and His-tag is produced in \u003cem\u003eE. coli \u003c\/em\u003ecells and site-specifically biotinylated at AviTag with \u003ca rel=\"noopener\" title=\"BirA Biotin Protein Ligase, Recombinant | Specific Enzymatic Biotinylation\" href=\"https:\/\/amidbiosciences.com\/products\/recombinant-bira-biotin-ligase-in-vitro-biotinylation\" target=\"_blank\"\u003eBirA enzyme.\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCatalog # KRAS12V-B-301\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAvailable in 0.1 mg and \u003cstrong\u003e1.0 mg bulk packaging\u003c\/strong\u003e for scalable assay development\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThis product is for laboratory research use only. \u003c\/strong\u003e\u003c\/p\u003e","brand":"Amid Biosciences","offers":[{"title":"0.1 mg","offer_id":39336335409233,"sku":"KRAS12V-B-301-01","price":800.0,"currency_code":"USD","in_stock":true},{"title":"1.0 mg","offer_id":59460790812753,"sku":"KRAS12V-B-301-1","price":6000.0,"currency_code":"USD","in_stock":true},{"title":"0.05 mg","offer_id":59460790845521,"sku":"KRAS12V-B-301-005","price":500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/KRAS_G12V_Protein_Human_Recombinant_Biotinylated.png?v=1736453151"},{"product_id":"kras-g13d-protein-human-recombinant-biotinylated","title":"KRAS G13D Protein, Human, Recombinant, Biotinylated","description":"\u003cp\u003eRecombinant \u003cstrong\u003eKRAS G13D \u003c\/strong\u003eprotein\u003cstrong\u003e \u003c\/strong\u003ewith the N-terminal AviTag™ peptide and His-tag is produced in \u003cem\u003eE. coli \u003c\/em\u003ecells and a site-specifically biotinylated with \u003ca href=\"https:\/\/amidbiosciences.com\/products\/bira-biotin-ligase-in-vitro-biotynilation\" title=\"BirA Enzyme\"\u003eBirA enzyme\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCatalog # KRAS13D-B-301\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThis product is for laboratory research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"0.1 mg","offer_id":39336337080401,"sku":"KRAS13D-B-301-1","price":800.0,"currency_code":"USD","in_stock":true},{"title":"1.0 mg","offer_id":59460790714449,"sku":"KRAS13D-B-301-2","price":6000.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/KRAS_G13D_Protein_Human_Recombinant_Biotinylated.png?v=1736454044"},{"product_id":"raf1-rbd-protein-human-recombinant","title":"Raf1 RBD Protein, Human, Recombinant","description":"\u003cp data-mce-fragment=\"1\"\u003eHuman Ras Binding Domain (RBD) of \u003cstrong\u003eRaf-1 Proto-Oncogene\u003c\/strong\u003e, Serine\/Threonine Kinase (RAF1), (UniProt # P04049, amino acids 1-149), expressed with an N-terminal 6XHis and glutathione S-transferase (GST) dual tag in E. coli. The dual 6xHis-GST tag allows immobilization of \u003cstrong\u003eRaf1 RBD Protein\u003c\/strong\u003e and RBD-Ras complexes on either Ni-NTA or glutathione agarose resin columns. \u003c\/p\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"0.1 mg","offer_id":39336367489105,"sku":"RAF1-301-1","price":280.0,"currency_code":"USD","in_stock":true},{"title":"1.0 mg","offer_id":59537104109649,"sku":"RAF1-301-2","price":2200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/Raf1_RBD_Protein_Human_Recombinant.png?v=1736282184"},{"product_id":"hrv-3c-protease-recombinant","title":"HRV 3C Protease, Recombinant, HisTag | Affinity Tag Removal","description":"\u003cp\u003eAmid Biosciences HRV 3C protease is a recombinant cysteine protease derived from human Rhinovirus type 14. The enzyme is known as PreScission Protease. HRV 3C protease specifically cleaves between the Gln and Gly residues of the recognition sequence \u003cstrong data-mce-fragment=\"1\"\u003eLeuGluValLeuPheGln\/GlyPro\u003c\/strong\u003e. Besides the recognition sequence, the secondary and tertiary structures of the fusion protein influence on substrate recognition and cleavage.\u003cbr\u003eThe recombinant enzyme is a 21 kDa protein with polyhistidine (6xHis) tag, so it can be removed from the protease reaction solution through immobilized metal affinity chromatography (IMAC).\u003cbr\u003e\u003c\/p\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"100 Units","offer_id":39492973428817,"sku":"HRV3C-301-1","price":80.0,"currency_code":"USD","in_stock":true},{"title":"500 Units","offer_id":59537077010513,"sku":"HRV3C-301-5","price":250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/HRV_3C_Protease_Recombinant_HisTag_Affinity_Tag_Removal.png?v=1736368323"},{"product_id":"kras-g12r-protein-human-recombinant-avitag","title":"KRAS G12R Protein, Human, Recombinant, AviTag","description":"\u003cp data-mce-fragment=\"1\"\u003eRecombinantÊ\u003cstrong data-mce-fragment=\"1\"\u003eKRAS G12RÊ\u003c\/strong\u003eprotein\u003cstrong data-mce-fragment=\"1\"\u003eÊ\u003c\/strong\u003ewith the N-terminal AviTagª peptide and His-tag is produced inÊ\u003cem data-mce-fragment=\"1\"\u003eE. coli\u003c\/em\u003e cells. Presence of AviTagª peptide can be useful for a site-specific biotinylation with \u003ca href=\"https:\/\/amidbiosciences.com\/products\/bira-biotin-ligase-in-vitro-biotynilation\" target=\"_blank\" title=\"BirA Biotin Ligase | In-vitro Biotinylation | Site-specific | High Activity\" rel=\"noopener\"\u003eBirA enzyme\u003c\/a\u003e.\u003c\/p\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"0.1 mg","offer_id":39737822511185,"sku":"KRAS12R-301","price":500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/KRAS_G12R_Protein_Human_Recombinant_AviTag.png?v=1736454709"},{"product_id":"kras-y96d-protein-human-recombinant-biotinylated","title":"KRAS Y96D Protein, Human, Recombinant, Biotinylated","description":"\u003cp data-mce-fragment=\"1\"\u003eRecombinantÊ\u003cstrong data-mce-fragment=\"1\"\u003eKRAS Y96DÊ\u003c\/strong\u003eprotein\u003cstrong data-mce-fragment=\"1\"\u003eÊ\u003c\/strong\u003ewith the N-terminal AviTagª peptide and His-tag is produced inÊ\u003cem data-mce-fragment=\"1\"\u003eE. coli\u003c\/em\u003e cells and site-specifically biotinylated at AviTag with \u003ca href=\"https:\/\/amidbiosciences.com\/products\/bira-biotin-ligase-in-vitro-biotinylation\" target=\"_blank\" title=\"BirA Biotin Ligase | In-vitro Biotinylation | Site-specific | High Activity\" rel=\"noopener\"\u003eBirA enzyme.\u003c\/a\u003e\u003c\/p\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"0.1 mg","offer_id":39737859407953,"sku":"KRAS96D-B-301","price":800.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/KRAS_Y96D_Protein_Human_Recombinant_Biotinylated.png?v=1736454509"},{"product_id":"sos1-protein-human-recombinant","title":"SOS1 Protein, Human, Recombinant | GTP Exchange | GEF Activity |Amid Biosciences","description":"\u003cp\u003e\u003cstrong\u003eSOS1\u003c\/strong\u003e, also known as son of sevenless homolog 1, is a Ras and Rac guanine nucleotide exchange factor (GEF). SOS1 binds and activates GDP-bound RAS family proteins at its catalytic binding site and in this way promotes exchange of GDP for GTP. Depletion of SOS1 or specific genetic inactivation of its GEF function has been shown to decrease the survival of tumor cells harboring a KRAS mutation (1).\u003c\/p\u003e\n\u003cp\u003eThe recombinant protein (amino acids 563-1049 of human SOS1) contains two domains, REM (Ras Exchanger Motif) and CDC25 (cell division cycle 25). CDC25 activates Ras and promotes nucleotide exchange on Ras proteins (2). The REM domain contains an activating allosteric site which binds Ras-GTP leading to additional stimulation of the CDC25 domain and potentiating the Ras-GTP exchange stimulated by SOS1.\u003c\/p\u003e\n\u003cp\u003eThe human SOS1 (Lys563-Thr1049) fragment with a polyhistidine tag at the C-terminus was expressed in E. coli.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eStudy inhibitors of SOS1 GTP exchange activity\u003c\/li\u003e\n\u003cli\u003eIdentification of SOS1 binding proteins\u003c\/li\u003e\n\u003cli\u003eStudy of SOS1 GEF activity with different GTPases\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eCatalog# SOS1-301\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThis product is for research use only. \u003c\/strong\u003e\u003c\/p\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"0.1 mg","offer_id":39751737081937,"sku":"SOS1-301-1","price":350.0,"currency_code":"USD","in_stock":true},{"title":"1.0 mg","offer_id":59537138090065,"sku":"SOS1-301-2","price":1800.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/SOS1_Protein_Human_Recombinant.png?v=1736281913"},{"product_id":"shp2-protein-human-recombinant-biotinylated","title":"SHP2 Protein, Human, Recombinant, Biotinylated | Amid Biosciences","description":"\u003cp\u003eSHP2, a Src homology 2 (SH2) domain containing non-transmembrane protein tyrosine phosphatase (PTP), is involved in a variety of signal transduction processes, such as the Ras-Raf-MAP kinase, Jak-Stat, and PI3 kinase pathways (1). Experimental data have also indicated SHP2 as a direct activator of Ras and a potential therapeutic target for cancers driven by oncogenic or hyperactive Ras variants (2, 3).\u003c\/p\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003eAvailable in 0.1 mg and \u003cstrong\u003e1.0 mg bulk packaging\u003c\/strong\u003e for scalable assay development.\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eFor Research Use Only (RUO).\u003c\/strong\u003e\u003cspan\u003e\u003cstrong\u003e \u003c\/strong\u003eThis product is for research use only. It is not intended for diagnostic or therapeutic use in humans or animals.\u003c\/span\u003e\u003c\/p\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"0.1 mg","offer_id":40021299822673,"sku":"SHP2-301-0.1","price":800.0,"currency_code":"USD","in_stock":true},{"title":"1.0 mg","offer_id":59537124130897,"sku":"SHP2-B-301-1","price":5000.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/SHP2-Protein-Human-Recombinant-Biotinylated.png?v=1780523165"},{"product_id":"raf1-rbd-50-140-protein-human-recombinant-biotinylated","title":"Raf1 RBD Protein, Human, Recombinant, Biotinylated","description":"\u003cp data-mce-fragment=\"1\"\u003eRas Binding Domain (RBD) of Human Raf-1 Proto-Oncogene, Serine\/Threonine Kinase (RAF1), (UniProt # P04049, amino acids 50-140) with the N-terminal AviTagª peptide and His-tag is produced inÊ\u003cem data-mce-fragment=\"1\"\u003eE. coli\u003c\/em\u003e cells and site-specifically biotinylated at AviTag with \u003ca rel=\"noopener\" title=\"BirA Biotin Ligase | In-vitro biotinylation | Site-specific | High Efficiency\" href=\"https:\/\/amidbiosciences.com\/products\/bira-biotin-ligase-in-vitro-biotynilation\" target=\"_blank\"\u003eBirA enzyme\u003c\/a\u003e.\u003c\/p\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"0.1 mg","offer_id":40221648781393,"sku":"RAF1-B-301","price":800.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/Raf1_RBD_Protein_Human_Recombinant_Biotinylated.png?v=1736282036"},{"product_id":"recombinant-human-saposin-c-protein","title":"Saposin C, Human, Recombinant","description":"\u003cp\u003e\u003cstrong\u003eSaposin C\u003c\/strong\u003e (SAP-C) is a small, heat-stable lysosomal glycoprotein derived from the prosaposin precursor protein via site-specific proteolytic cleavage. Among the four prosaposin-derived domains, Saposin C shares high structural homology with Saposin A and acts as an indispensable biological cofactor required for the lysosomal activation of β-glucocerebrosidase (GBA)—the enzyme deficient in Gaucher disease. Additionally, Saposin C plays a critical role in cellular immunology by facilitating the presentation of lipid antigens through CD1b molecules to human T cells. While native lysosomal saposins are heavily glycosylated, non-glycosylated recombinant variants expressed in bacterial systems maintain full biological activation properties in functional \u003cem\u003ein vitro\u003c\/em\u003e biochemical assays.\u003c\/p\u003e\n\u003ch3\u003eKey Applications \u0026amp; SapC-DOPS Nanocarriers\u003c\/h3\u003e\n\u003cp\u003eBeyond its role in sphingolipid catabolism, recombinant Saposin C is widely utilized in translational oncology research. It can be assembled with dioleoylphosphatidylserine to form \u003cstrong\u003eSapC-DOPS\u003c\/strong\u003e, a highly selective, membrane-targeted nanocarrier platform used to target and induce apoptosis in various cancer models, including glioblastoma multiforme. This makes high-purity, tag-free Saposin C an essential reagent for drug delivery innovation, lipid metabolism studies, and vaccine adjuvant formulation.\u003c\/p\u003e\n\u003ch3\u003eProduct Features \u0026amp; Specifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eExpression System:\u003c\/strong\u003e Engineered and expressed in an optimized \u003cem\u003eEscherichia coli\u003c\/em\u003e (\u003cem\u003eE. coli\u003c\/em\u003e) bacterial host.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTag Status:\u003c\/strong\u003e Expressed as an N-terminal His-tag fusion and purified using proprietary chromatography steps, followed by site-specific proteolytic cleavage to yield a completely \u003cstrong\u003etag-free\u003c\/strong\u003e final protein.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHigh Purity:\u003c\/strong\u003e Verified at \u0026gt;90% purity by Coomassie blue staining on SDS-PAGE.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence Profile:\u003c\/strong\u003e Native mature Saposin C sequence (SDVYCEVCEF...SG).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation \u0026amp; Storage:\u003c\/strong\u003e Supplied at a concentration of 1.0 mg\/mL (determined by A280) in 10 mM Tris-HCl, pH 7.5, 100 mM NaCl, and 50% Glycerol. Store securely at -20°C.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003e\u003cem\u003eCatalog Number: SAPC-302-1 | \u003cstrong\u003eThis product is intended for laboratory research use only (RUO).\u003c\/strong\u003e Product requires shipping on ice packs.\u003c\/em\u003e\u003c\/small\u003e\u003c\/p\u003e","brand":"Amid Biosciences","offers":[{"title":"0.1 mg","offer_id":40280463605841,"sku":"SAPC-302-1","price":900.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/Saposin_C_Human_Recombinant.png?v=1779506672"},{"product_id":"recombinant-human-saposin-d-protein","title":"Saposin D, Human, Recombinant","description":"\u003cp\u003e\u003cstrong\u003eSaposin D\u003c\/strong\u003e (SAP-D) is a small, heat-stable lysosomal glycoprotein derived from the prosaposin precursor protein via site-specific proteolytic cleavage. It functions as an indispensable non-enzymatic cofactor required for the lysosomal breakdown of ceramides into free fatty acids and sphingosine by acid ceramidase (ASAH1). Deficiencies in functional Saposin D or its cognate enzyme lead to severe ceramide accumulation, causing lysosomal storage disorders such as Farber lipogranulomatosis. While native saposins feature complex glycosylation patterns, non-glycosylated recombinant saposins expressed in bacterial systems retain full biological activation properties in functional \u003cem\u003ein vitro\u003c\/em\u003e biochemical and lipid reconstitution assays.\u003c\/p\u003e\n\u003ch3\u003eKey Research \u0026amp; Assay Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCeramide Catabolism \u0026amp; Enzymology:\u003c\/strong\u003e Functions as a vital cofactor for reconstituting \u003cem\u003ein vitro\u003c\/em\u003e acid ceramidase enzyme kinetics and lipid-cleaving mechanics.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLipidomics \u0026amp; Membrane Biophysics:\u003c\/strong\u003e Used in downstream structural biochemistry profiling to study protein-lipid bilayer interactions and membrane permeabilization.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTherapeutic \u0026amp; Chaperone Screening:\u003c\/strong\u003e High-value target component for screening small molecule chaperones, enzyme replacement therapies (ERT), or drug designs targeting Farber disease pathways.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eProduct Features \u0026amp; Specifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eExpression System:\u003c\/strong\u003e Engineered and produced in an optimized \u003cem\u003eEscherichia coli\u003c\/em\u003e (\u003cem\u003eE. coli\u003c\/em\u003e) bacterial expression platform.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTag Status:\u003c\/strong\u003e Expressed as an N-terminal His-tag fusion and purified using proprietary chromatography steps, followed by site-specific proteolytic cleavage to yield a completely \u003cstrong\u003etag-free\u003c\/strong\u003e final protein.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHigh Purity:\u003c\/strong\u003e Formulated to \u0026gt;90% purity as verified by Coomassie blue staining on SDS-PAGE.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage Buffer:\u003c\/strong\u003e Supplied at a concentration of 0.5 – 2.0 mg\/mL in 10 mM Tris-HCl, pH 7.5, 100 mM NaCl, and 50% Glycerol for premium structural stability.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003e\u003cem\u003eCatalog Number: SAPD-301-1 | \u003cstrong\u003eThis product is intended for laboratory research use only (RUO). \u003c\/strong\u003eProduct requires shipping on ice packs.\u003c\/em\u003e\u003c\/small\u003e\u003c\/p\u003e","brand":"Amid Biosciences","offers":[{"title":"0.1 mg","offer_id":40280464851025,"sku":"SAPD-301-1","price":900.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/Saposin_D_Human_Recombinant.png?v=1779506289"},{"product_id":"rnase-inhibitor-murine-recombinant","title":"RNase Inhibitor, Murine, Recombinant","description":"\u003cp\u003eMurine RNAse Inhibitor is a potent inhibitor of ribonucleases such as RNase A, RNase B, and RNase C. Murine RNase Inhibitor is resistant to oxidation compared to the human\/porcine RNase inhibitors since it lacks the pair of cysteines found in the human\/porcine versions. In addition, it is stable at less than 1 mM DTT concentration, and this property makes it useful for reactions where low concentration DTT is necessary to the reaction.\u003c\/p\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"5000 Units","offer_id":40280471240785,"sku":"RIM-301-1","price":90.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/RNase_Inhibitor_Murine_Recombinant.png?v=1736368897"},{"product_id":"phi69-dna-polymerase","title":"phi29 DNA Polymerase","description":"\u003cp\u003ephi29 DNA polymerase is the replicative polymerase from theÊBacillus subtilisÊphage phi29 (_29). It is an extremely processive DNA polymerase (up to 70 kb per binding event) with extraordinary strand displacement capacity, exhibiting 3Õ _ 5Õ proofreading exonuclease activity, resulting in an exceptionally high synthesis fidelity.\u003c\/p\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"1000 Units","offer_id":40287236620369,"sku":"PHDP-301-1","price":140.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/phi69_DNA_Polymerase.png?v=1736368840"},{"product_id":"g12v-kras1-166-biotinylated-at-the-c-terminus","title":"G12V KRAS(1-166), Biotinylated at the C-terminus","description":"\u003cp data-mce-fragment=\"1\"\u003eRecombinantÊ\u003cstrong data-mce-fragment=\"1\"\u003eKRAS G12VÊ\u003c\/strong\u003eprotein\u003cstrong data-mce-fragment=\"1\"\u003eÊ\u003c\/strong\u003ewith the C-terminal AviTagª peptide and His-tag is produced inÊ\u003cem data-mce-fragment=\"1\"\u003eE. coli\u003c\/em\u003e cells and site-specifically biotinylated at AviTag with \u003ca href=\"https:\/\/amidbiosciences.com\/products\/bira-biotin-ligase-in-vitro-biotinylation\" target=\"_blank\" title=\"BirA Biotin Ligase | In-vitro Biotinylation | Site-specific | High Activity\" rel=\"noopener\"\u003eBirA enzyme.\u003c\/a\u003e\u003c\/p\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"0.1 mg","offer_id":40287281971281,"sku":"KRAS12V-B-C-301","price":800.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/G12V_KRAS_1-166_Biotinylated_at_the_C-terminus.png?v=1736453966"},{"product_id":"rheb-protein-human-recombinant-biotinylated","title":"Rheb Protein, Human, Recombinant, Biotinylated","description":"\u003cp\u003eRheb (\u003cspan\u003e\u003cu\u003eR\u003c\/u\u003e\u003c\/span\u003easÊ\u003cspan\u003e\u003cu\u003eh\u003c\/u\u003e\u003c\/span\u003eomologÊ\u003cspan\u003e\u003cu\u003ee\u003c\/u\u003e\u003c\/span\u003enriched inÊ\u003cspan\u003e\u003cu\u003eb\u003c\/u\u003e\u003c\/span\u003erain) is a small GTPase that functions as an important mediator between the tumor suppressor proteins TSC1. Rheb shares about 30Ð40% sequence identity with members of the Ras\/Rap subfamily of small GTPases. Human Rheb consists of 184 amino acid residues. The 169 N-terminal residues form the GTPase domain; the 15 C-terminal residues are hypervariable with a flexible structure and comprise a conserved carboxyl CAA\u003cem\u003eX\u003c\/em\u003eÊmotif that plays important roles in the farnesylation of Rheb and its association with membrane (1).\u003c\/p\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"0.1 mg","offer_id":40329244999761,"sku":"RHEB-B-301","price":800.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/Rheb_Protein_Human_Recombinant_Biotinylated.png?v=1736282329"},{"product_id":"rala-protein-human-recombinant-biotinylated","title":"RalA Protein, Human, Recombinant, Biotinylated","description":"\u003cp\u003eRas-related protein Ral-A (RALA) is a member of the Ras GTPaseÊfamily and shares a high structural similarity with RAS proteins (1). In human cells, the two protein isoforms, RALA and RALB, have been shown to play roles in the proliferation, survival, and metastasis of a variety of human cancers. RALA and RALB share 81% sequence homology with one another and more than 50% sequence homology with RAS. Given their importance in cancer biology, RAL proteins have emerged as desirable clinical targets (2).\u003c\/p\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"0.1 mg","offer_id":40355811033169,"sku":"RALA-B-301","price":800.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/RalA_Protein_Human_Recombinant_Biotinylated.png?v=1736282252"},{"product_id":"ralb-protein-human-recombinant-biotinylated","title":"RalB Protein, Human, Recombinant, Biotinylated","description":"\u003cp\u003eRas-related protein Ral-B (RALB) is a member of the Ras GTPaseÊfamily and shares a high structural similarity with RAS proteins (1). In human cells, the two protein isoforms, RALA and RALB, have been shown to play roles in the proliferation, survival, and metastasis of a variety of human cancers. RALA and RALB share 81% sequence homology with one another and more than 50% sequence homology with RAS. Given their importance in cancer biology, RAL proteins have emerged as desirable clinical targets (2).\u003c\/p\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"0.1 mg","offer_id":40355811229777,"sku":"RALB-B-301","price":800.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/RalB_Protein_Human_Recombinant_Biotinylated.png?v=1736282491"},{"product_id":"sirtuin-5-human-recombinant-biotinylated","title":"Sirtuin 5 (SIRT5), Human, Recombinant, Biotinylated","description":"\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eSIRT5 (Sirtuin 5)\u003c\/strong\u003e is a member of the SIR2 \/ Sirtuin family of nicotinamide adenine dinucleotide (NAD+)-dependent deacetylase enzymes. Sirtuin family enzymes can be found in the cytoplasm, mitochondria or nucleus of a cell and are ubiquitously expressed. SIRT5 has multiple enzymatic functions, such as NAD+-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. \u003c\/p\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"0.1 mg","offer_id":40379940634705,"sku":"SIRT5-B-301","price":800.0,"currency_code":"USD","in_stock":true},{"title":"1.0 mg","offer_id":59537126195281,"sku":"SIRT5-B-301-1","price":6000.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/Sirtuin_5_Human_Recombinant_Biotinylated.png?v=1736369883"},{"product_id":"teln-protelomerase-recombinant","title":"TelN Protelomerase, Recombinant | Amid Biosciences","description":"\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong\u003eTelN Protelomerase\u003c\/strong\u003e from E. coli bacteriophage N15Ê\u003cspan data-mce-fragment=\"1\"\u003eprocesses circular and linear plasmid DNA containing the target siteÊ\u003c\/span\u003e\u003cem data-mce-fragment=\"1\"\u003etelRL\u003c\/em\u003e\u003cspan data-mce-fragment=\"1\"\u003eÊto produce linear double-stranded DNA with covalently closed ends. The 56-bpÊ\u003c\/span\u003e\u003cem data-mce-fragment=\"1\"\u003etelRL\u003c\/em\u003e\u003cspan data-mce-fragment=\"1\"\u003eÊtarget site consists of a centralÊ\u003c\/span\u003e\u003cem data-mce-fragment=\"1\"\u003etelO\u003c\/em\u003e\u003cspan data-mce-fragment=\"1\"\u003eÊ palindrome of 22 bp and two 14-bp flanking sequences comprising inverted repeats.Ê\u003c\/span\u003e\u003cem data-mce-fragment=\"1\"\u003etelO\u003c\/em\u003e\u003cspan data-mce-fragment=\"1\"\u003eÊis separated from these repeats by 3 bp on each side. TheÊ\u003c\/span\u003e\u003cem data-mce-fragment=\"1\"\u003etelRL\u003c\/em\u003e\u003cspan data-mce-fragment=\"1\"\u003eÊsequence is sufficient for TelN-mediated processing.\u003c\/span\u003e TelN has cutting-ligating enzyme activity and covalently ligates at the cleavage site forming hairpin termini.\u003c\/p\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"1000 Units","offer_id":40379952955473,"sku":"TELN-301-2","price":270.0,"currency_code":"USD","in_stock":true},{"title":"250 Units","offer_id":59537197170769,"sku":"TELN-301-1","price":70.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/TelN_Protelomerase_Recombinant.png?v=1736369524"},{"product_id":"mek1-protein-human-recombinant-biotinylated","title":"MEK1 Protein, Human, Recombinant, Biotinylated | Amid Biosciences","description":"\u003cp\u003eMEK1 is a dual specificity protein kinase, which is known as a mitogen-activated protein (MAP) kinase kinase 1 (MAPKK 1). MAP kinases are recognized as extracellular signal-regulated kinases (ERKs) that act as an integration position for multiple biochemical signals. MEK1 is located upstream of MAP kinases and catalyzes phosphorylation of threonine and tyrosine residues on MAP kinases ERK1 and ERK2. MEK1 is activated by phosphorylation of serine 218 and 222 residues by Raf1. As a key player of the MAP kinase signal transduction pathway, MEK1 is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.\u003cbr\u003e\u003c\/p\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"0.05 mg","offer_id":40383132336209,"sku":"MEK1-B-301","price":900.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/MEK1_Protein_Human_Recombinant_Biotinylated.png?v=1736282413"},{"product_id":"products-biotinylated-human-trem-1-protein-recombinant","title":"TREM-1 Protein, Human, Recombinant, Biotinylated","description":"\u003cp\u003e\u003cstrong\u003eTREM-1\u003c\/strong\u003e (Triggering Receptor Expressed on Myeloid Cells 1) is a critical cell surface receptor belonging to the immunoglobulin superfamily. It is predominantly expressed on blood granulocytes, monocytes, and activated macrophages, where it acts to amplify inflammatory responses triggered by bacterial and fungal infections. Beyond acute infection, TREM-1 plays a pivotal role in chronic inflammatory pathways, particularly in the pathophysiology of inflammatory bowel disease (IBD), rheumatoid arthritis, and metabolic inflammation. Interrogating the TREM-1 signaling cascade is a primary focus for therapeutic antibody screening, small molecule inhibition, and biomarker validation campaigns.\u003c\/p\u003e\n\n\u003ch3\u003eProduct Features \u0026amp; Specifications\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\n\u003cstrong\u003eExpression Host:\u003c\/strong\u003e Engineered and produced using a high-yield \u003cem\u003eE. coli\u003c\/em\u003e bacterial expression system.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eAmino Acid Sequence:\u003c\/strong\u003e Represents the extracellular domain of human TREM-1 (amino acids 21–205; UniProt ID: Q9NP99-1).\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eFusion Tags:\u003c\/strong\u003e Features a C-terminal AviTag™ peptide sequence alongside a C-terminal 6xHis tag for streamlined detection and capture.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003ePrecision Biotinylation:\u003c\/strong\u003e Site-specifically biotinylated at the AviTag™ sequence using BirA enzyme, preserving the native structural conformation of the binding interface.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eMolecular Mass:\u003c\/strong\u003e Resolves at approximately ~24 kDa under reducing conditions.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eHigh Purity:\u003c\/strong\u003e Formulated to \u0026gt;90% purity as verified by Coomassie blue staining on SDS-PAGE.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eStorage Buffer:\u003c\/strong\u003e Supplied in 20 mM Tris-HCl, pH 7.5, 100 mM NaCl, 10% glycerol for optimal long-term stability.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eValidated Applications\u003c\/h3\u003e\n\u003cp\u003eThis site-specifically biotinylated TREM-1 construct is optimized for robust performance in functional target-binding assays, high-throughput screening (HTS) of neutralizing biologics, surface plasmon resonance (SPR), bio-layer interferometry (BLI), and streptavidin-coated plate ELISA formats.\u003c\/p\u003e\n\n\u003cp\u003e\u003csmall\u003e\u003cem\u003eCatalog Number: TREM1-B-301 | This product is for research use only (RUO). Not intended for human diagnostic or therapeutic applications.\u003c\/em\u003e\u003c\/small\u003e\u003c\/p\u003e","brand":"Amid Biosciences","offers":[{"title":"0.1 mg","offer_id":40387863773265,"sku":"TREM1-B-301","price":900.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/TREM-1_Protein_Human_Biotinylated.png?v=1779484867"},{"product_id":"wild-type-kras-protein-human-recombinant-biotinylated-without-a-his-tag","title":"Wild Type KRAS Protein, Human, Biotinylated, Without a His-tag","description":"\u003cp class=\"MsoNormal\"\u003e\u003cspan style=\"font-size: 11.0pt; font-family: 'Arial',sans-serif;\"\u003eRecombinantÊ\u003cb\u003eKRASÊ\u003c\/b\u003eprotein with the N-terminal AviTagª peptide is produced inÊ\u003ci\u003eE. coli\u003c\/i\u003e cells and site-specifically biotinylated at AviTag with \u003ca href=\"https:\/\/amidbiosciences.com\/products\/bira-biotin-ligase-in-vitro-biotynilation\" title=\"BirA Biotin Ligase | In-vitro Biotinylation | Site-specific | High Activity\" rel=\"noopener\" target=\"_blank\"\u003eBirA enzyme\u003c\/a\u003e.\u003c\/span\u003e\u003c\/p\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"0.1 mg","offer_id":40505107218513,"sku":"KRAS-B-302","price":1200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/Wild_Type_KRAS_Protein_Human_Biotinylated_Without_a_His-tag.png?v=1736454446"},{"product_id":"kras-g12v-protein-human-biotinylated-without-a-his-tag","title":"KRAS G12V Protein, Human, Biotinylated, Without a His-tag","description":"\u003cp class=\"MsoNormal\"\u003e\u003cspan style=\"font-size: 11.0pt; font-family: 'Arial',sans-serif;\"\u003eRecombinantÊ\u003cb\u003eKRASÊG12V \u003c\/b\u003eprotein with the N-terminal AviTagª peptide is produced inÊ\u003ci\u003eE. coli\u003c\/i\u003e cells and site-specifically biotinylated at AviTag with \u003ca href=\"https:\/\/amidbiosciences.com\/products\/bira-biotin-ligase-in-vitro-biotinylation\" target=\"_blank\" title=\"BirA Biotin Ligase | In-vitro Biotinylation | Site-specific | High Activity\" rel=\"noopener\"\u003eBirA enzyme\u003c\/a\u003e.\u003c\/span\u003e\u003c\/p\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"0.1 mg","offer_id":40505107513425,"sku":"KRAS12V-B-302","price":1200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/KRAS_G12V_Protein_Human_Biotinylated_Without_a_His-tag.png?v=1736454390"},{"product_id":"senp2-protease-human-recombinant","title":"SenP2 Protease, Human, Recombinant | Amid Biosciences","description":"\u003cp\u003e\u003cstrong\u003eSenP2 Protease (sentrin-specific protease 2)\u003c\/strong\u003e is a highly active recombinant enzyme that catalyzes the deconjugation of SUMO1, SUMO2, and SUMO3 peptides from targeted proteins, making it an essential tool for SUMO-tag removal and functional protein expression studies.\u003c\/p\u003e\n\n\u003ch3\u003eKey Features \u0026amp; Specifications:\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\n\u003cstrong\u003eSource \u0026amp; Expression Host:\u003c\/strong\u003e Escherichia coli (E. coli)\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eExpressed Region:\u003c\/strong\u003e Asp363-Leu589 (UniProt: Q9HC62-1)\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eTagging:\u003c\/strong\u003e His-tag (N-terminus) for easy downstream removal or detection\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e \u0026gt;90% as determined by Coomassie staining\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Supplied in 20 mM Tris-HCl, pH 7.5, 100 mM NaCl, 5 mM 2-mercaptoethanol, and 50% glycerol\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e ~29 kDa\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eApplications:\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003eHighly efficient cleavage of SUMO-fusion proteins\u003c\/li\u003e\n  \u003cli\u003eDeubiquitinating and deSUMOylating activity assays\u003c\/li\u003e\n  \u003cli\u003ePost-translational modification (PTM) analysis\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003e\u003cstrong\u003eCatalog #:\u003c\/strong\u003e SNP2-301\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eApplication Disclaimer:\u003c\/strong\u003e For Research Use Only (RUO). This product is for research use only and is not intended for diagnostic or therapeutic use in humans or animals.\u003c\/em\u003e\u003c\/p\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"0.05 mg","offer_id":40663997317201,"sku":"SNP2-301-0.05","price":300.0,"currency_code":"USD","in_stock":true},{"title":"0.1 mg","offer_id":59537137500241,"sku":"SNP2-301-0.1","price":480.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/SenP2_Protease_Human_Recombinant.png?v=1736368257"},{"product_id":"kras-g12c-y96d-protein-human-recombinant-biotinylated","title":"KRAS G12C, Y96D Protein, Human, Recombinant, Biotinylated","description":"\u003cp\u003e\u003cstrong\u003eKRAS G12C\/Y96D \u003c\/strong\u003edouble mutant displays resistance to multiple KRAS G12C inhibitors currently in clinical development (1). Recombinant \u003cstrong\u003eKRAS G12C\/Y96D \u003c\/strong\u003eprotein with the N-terminal AviTag\u003cmeta charset=\"utf-8\"\u003e\u003cb data-index-in-node=\"18\" data-path-to-node=\"6,0,0\"\u003e™\u003c\/b\u003e peptide and His-tag is produced in \u003cem\u003eE. coli\u003c\/em\u003e cells and site-specifically biotinylated at AviTag with \u003ca rel=\"noopener\" title=\"BirA Biotin Ligase | In-vitro Biotinylation | Site-specific | High Activity\" href=\"https:\/\/amidbiosciences.com\/products\/bira-biotin-ligase-in-vitro-biotinylation\" target=\"_blank\"\u003eBirA enzyme\u003c\/a\u003e.  \u003c\/p\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"0.1 mg","offer_id":41113491243089,"sku":"KRAS12C-96D-B-301","price":800.0,"currency_code":"USD","in_stock":true},{"title":"1.0 mg","offer_id":59460790681681,"sku":"KRAS12C-96D-B-302","price":6000.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/KRAS_G12C_Y96D_Protein_Human_Recombinant_Biotinylated.png?v=1736454272"},{"product_id":"biotinylated-human-galectin-3-protein-recombinant","title":"Galectin-3 Protein, Human, Recombinant, Biotinylated","description":"\u003cp\u003e\u003cstrong\u003eGalectin-3\u003c\/strong\u003e, also known as \u003cstrong\u003eLGALS3\u003c\/strong\u003e, is a prominent member of the beta-galactoside-binding animal lectin family. 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It downregulates the Ras signaling pathway by promoting the hydrolysis of the active form of Ras (GTP-bound Ras) to an inactive form of Ras (GDP-bound Ras) by increasing the intrinsic GTPase activity of Ras (1).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eFor Research Use Only (RUO).\u003c\/strong\u003e\u003cspan\u003e\u003cstrong\u003e \u003c\/strong\u003eThis product is for research use only. It is not intended for diagnostic or therapeutic use in humans or animals.\u003c\/span\u003e\u003c\/p\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"0.05 mg","offer_id":41917780131921,"sku":"NF1-301","price":900.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/Neurofibromin_NF1_Human_Recombinant_Amid_Biosciences.png?v=1777752601"},{"product_id":"t4-rna-ligase-2","title":"T4 RNA Ligase 2","description":"\u003cp style=\"margin-bottom: 0in; line-height: normal; background: white; vertical-align: baseline;\" class=\"MsoNormal\"\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; color: #2a2a2a;\"\u003e\u003cstrong\u003eT4 RNA Ligase 2\u003c\/strong\u003e, also known as T4 Rnl2 (gp24.1), has both intermolecular and intramolecular RNA strand joining activity. T4 RNA Ligase 2 is more active for joining nicks on double stranded RNA than on joining the ends of single stranded RNA. The enzyme requires an adjacent 5« phosphate and 3« OH for ligation. The enzyme can also ligate the 3« OH of RNA to the 5« phosphate of DNA in a double stranded structure. The non-ligated strand of the duplex can be either RNA or DNA. T4 RNA ligase 2 requires ATP for activity unless the substrate is preadenylated on the 5_ end.\u003c\/span\u003e\u003c\/p\u003e","brand":"Amid Biosciences | Protein Engineering Company","offers":[{"title":"200 Units","offer_id":41987176562769,"sku":"RNL2-301-1","price":90.0,"currency_code":"USD","in_stock":true},{"title":"1000 Units","offer_id":59537112629329,"sku":"RNL2-301-2","price":360.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/files\/T4_RNA_Ligase_2.png?v=1736369453"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0981\/2236\/collections\/BirA-450x450.jpg?v=1741624053","url":"https:\/\/amidbiosciences.com\/collections\/recombinant-proteins.oembed?page=5","provider":"Amid Biosciences","version":"1.0","type":"link"}